Search Results - bio-technology

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  1. Radiotherapy is a common medical procedure, especially for the treatment of cancers such as head and neck, breast prostate, lung and rectum. It is a complex process aimed at maximizing delivery of the planned dose to the tumor sites while minimizing unnecessary radiation to healthy tissues. Today, radiotherapy procedures make use of image guidance ...
    Published: 6/21/2017
  2. Production of monoclonal antibodies (mAbs) in plants has developed tremendously over the past two decades, in great part due to low production costs, scalability and lack of animal pathogen contamination. Rituximab is a chimeric monoclonal antibody against CD20 used in the treatment of lymphomas and leukemias. Rituximab has been FDA approved for t...
    Published: 6/21/2017
  3. Multinucleated giant cells (MGCs), formed from macrophage fusion, occur as a consequence of a number of pathological conditions in the body. MGC formation can be particularly destructive to synthetic implants, as it etches their surface, and could lead to implant failure. Despite significant research into macrophage fusion, there are many underlyi...
    Published: 6/12/2017
  4. Insulator-based dielectrophoresis (iDEP) is the motion of particles due to a force from a uniform electric field. IDEP is useful in the manipulation of particles, cells and even organelles. However, IDEP forces scale dependent upon the geometry, making separation, preconcentration and fractionation difficult to achieve large-scale. Furthermore, the...
    Published: 3/14/2017
  5. The ability to profile the genome and transcriptome, comprehensively, in single cells, in situ, is crucial to understanding the underlying mechanisms involved in cancer, neurobiology and stem cell biology. However, most of the existing tools can only quantify a small number of different nucleic acids in a sample and gene expression variations and s...
    Published: 1/11/2017
    Inventor(s): Jia Guo
  6. High speed mid-infrared (MIR) photodetectors are crucial in numerous applications, ranging from hyper-spectral imaging and biomedical sensing to environmental monitoring and astronomy. However, fundamental limitations in current technologies restrict the scope of use for these photodetectors. Current technologies suffer from weaknesses such as redu...
    Published: 12/24/2016
    Inventor(s): Yu Yao
  7. Aminoglycoside antibiotics are known to prevent growth of gram-negative bacteria by inhibiting protein synthesis. Aminoglycosides possess biocompatible sugar groups as well as multiple amines in the same molecule. Their tenability, biocompatibility and natural affinity towards biomolecules make them excellent candidates for generating diverse resin...
    Published: 12/15/2016
  8. Translational coupling is a form of gene regulation in which the translation of one protein influences another. It is widely used in prokaryotes to control the production of genes within a metabolic pathway, or in bacteriophages to efficiently regulate translation within their extremely compact genomes.Researchers at Arizona State University have d...
    Published: 11/28/2016
    Inventor(s): Alexander Green, Anli Tang
  9. Guidewires are used to navigate tortuous vessel anatomy and provide a stable guiding structure along which a catheter is advanced to its target within the body. Current guidewires come in a variety of stiffness for different applications; low stiffness wires enable easier steering and navigation and high stiffness wires enable stable catheter deliv...
    Published: 11/14/2016
  10. As a method for surgical repair, suturing is ubiquitous, and has changed little in modern medicine. Conventional suture techniques still have problems with friable and difficult to close tissues. Current suture alternatives, such as staples, clamps and adhesives, while offering convenience to the surgeon and quicker procedure times, still suffer fr...
    Published: 10/31/2016

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