Search Results - diagnostic assays/devices

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  1. Antibiotic resistance has become a significant public health threat. It causes billions of healthcare-related costs as well as 2 million hospitalizations and 23,000 deaths annually in the US alone. Clinical treatment of bacterial infections, especially in acute cases of sepsis, requires multiple steps, including antibiotic susceptibility testing (A...
    Published: 1/16/2018
  2. Cancer is one of the biggest challenges facing the present healthcare community. Cancer diagnostics play a very important role in detecting the onset of disease and enabling continuous monitoring of patients in remission. Early detection of disease occurrence, progression and/or recurrence can significantly increase the chances of patient survival....
    Published: 12/13/2017
  3. Antimicrobial resistance is one of the biggest global health crises we are currently facing, and it is being accelerated by the overuse and misuse of antibiotics. There is a tendency, especially in pediatrics, to prescribe antibiotics for viral infections, or to withhold an antibiotic out of an abundance of caution. A contributing factor in antibio...
    Published: 11/6/2017
    Inventor(s): Stephen Johnston, Lu Wang
  4. Wearable biomedical devices hold the promise of early detection, diagnosis, and treatment of a number of diseases. Because they are non-invasive, they have the potential to help patients and clinicians by providing continuous monitoring prior to the onset of more severe symptoms. These devices often utilize silicon wafer-based microelectronic compo...
    Published: 9/27/2017
    Keywords(s): Flexible electronics
  5. Devices that continuously monitor cardiac activity in free living conditions are being integrated into everyday life. Cardiac sensors are an essential advancement for disease diagnostics and evaluation of post-operative progress. Also, these observations are useful for overall physical health and well-being. With today’s technology, smartpho...
    Published: 9/18/2017
  6. Nanoscience is widely used today across a diverse product array. Applications such as food containers for improved product freshness, textile coatings for impact minimization, battery technologies for increased product life, cosmetics and genetic screening for drug compatibility are examples of commercial products that use nanotechnology. Nanotechn...
    Published: 9/11/2017
  7. Telomeres, tandem repeats at the ends of chromatids, are a particular point of interest in the science of aging and cancer. Telomeric DNA is lost during cellular replication, resulting in shortened chromatid length and cessation of cell division. Many age-related diseases are linked to shortened telomeres. Conversely, many cancer cells demonstrate ...
    Published: 6/21/2017
    Inventor(s): Fusheng Xiong, Wayne Frasch
  8. Immunotherapeutics, including Checkpoint inhibitors (CIs), show great promise in treating diseases including cancer, however, only a small percentage of patients respond well to these therapeutics. Because Immunotherapeutics are expensive and are associated with severe adverse side effects, screening is necessary to determine if a patient is likely...
    Published: 5/30/2017
    Inventor(s): Stephen Johnston
    Keywords(s): Diagnostics
  9. Nanotechnology needs organization and precise control, which is why DNA self-assembly into nanostructures has been a remarkable breakthrough. The challenges in creating nanostructures and also the opportunities lie in how to achieve self-sustained replication. This allows for the system to amplify itself in unlimited cycles, which is not enabled in...
    Published: 5/23/2017
    Inventor(s): Hao Yan
  10. Noninvasive sampling is critical for certain patient populations, such as hemophiliacs, neonates, elderly or immunocompromised individuals, especially if they require daily monitoring. Blood sampling is painful, inconvenient and often difficult and increases the risk of exposure to infectious agents, which can be devastating to immunocompromised po...
    Published: 4/14/2017

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